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BioForm Solutions > Articles > Fluorescence vs. Impedance Flow Cytometry for Probiotic Enumeration: Results from a Collaborative Inter-Laboratory Ring Test

Fluorescence vs. Impedance Flow Cytometry for Probiotic Enumeration: Results from a Collaborative Inter-Laboratory Ring Test

This review examines the complex challenge of accurately measuring probiotic viability and activity. The authors highlight that traditional CFU-based plate counts capture only a portion of viable microbial populations and may overlook metabolically active or stress-adapted cells. The paper emphasizes the importance of combining analytical approaches, including culture-independent methods, to better characterize probiotic functionality and product quality.